What is Bioinformatics
Bioinformatics is the application of computer technology
to the analysis and management of large-scale, complex biological data.
- Data analysis
- Data storage
- Data mining
- Knowledge discovery
- Biological modelling
Bioinformatics may be applied in:
And other fields.
- DNA and protein sequence analysis
- Differential gene expression
- Protein structure and function
- Protein interactions
- Biological networks
- Variation analysis
- Drug design
Goal: identify a disease gene
Situation: Gene mapped to a certain region, which is currently
being sequenced elsewhere.
Strategy: Retrieve new sequences as they are published and look for known or new genes. Test the found genes for relevance to the disease.
Repeat the following steps every week:
Note that for steps 2 and 3 you may use existing bioinformatics tools.
- Data retrieval
- Identification of known gene(s) by database search
- Identification of new gene(s) using gene prediction programs
- Storage of results
- Experimental examination of the found gene(s)
Write a computer program to automate steps 1 - 4.
Table of Contents.